Reactome | Metabolism of vitamin K

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Metabolism of vitamin K Show undefined attributes

created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10729046
displayName	Metabolism of vitamin K
eventOf	[Pathway:R-XTR-6806667] Metabolism of fat-soluble vitamins - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:11306] vitamin K metabolic process
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-XTR-6806674] UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) - Xenopus tropicalis [Reaction:R-XTR-9026967] VKORC1 inhibitors binds VKORC1 dimer - Xenopus tropicalis [Reaction:R-XTR-159790] VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) - Xenopus tropicalis [Reaction:R-XTR-6806647] VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) - Xenopus tropicalis
inferredFrom	[Pathway:R-HSA-6806664] Metabolism of vitamin K - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Metabolism of vitamin K
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-6806664
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-6806667] Metabolism of fat-soluble vitamins
(inferredTo)	[Pathway:R-HSA-6806664] Metabolism of vitamin K
(hasEncapsulatedEvent)	[Pathway:R-XTR-163841] Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation

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