Reactome | MAPK4,6 translocate to the cytoplasm

Schema > BlackBoxEvent > Entries

category	omitted
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10702510
displayName	MAPK4,6 translocate to the cytoplasm
eventOf	[Pathway:R-XTR-5687128] MAPK6/MAPK4 signaling - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-5687109] MAPK4,6 translocate to the cytoplasm - Homo sapiens
input	[DefinedSet:R-XTR-5692704] MAPK4,6 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	MAPK4,6 translocate to the cytoplasm
output	[DefinedSet:R-XTR-5692706] MAPK4,6 [cytosol]
regulatedBy	[Requirement:10702511] Requirement by 'XPO1 [nucleoplasm]'
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-5687109
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-XTR-5687128] MAPK6/MAPK4 signaling
(inferredTo)	[BlackBoxEvent:R-HSA-5687109] MAPK4,6 translocate to the cytoplasm

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