Reactome | phospho-chek2 [nucleoplasm]

Schema > EntityWithAccessionedSequence > Entries

catalystActivities	[CatalystActivity:10652483] protein serine/threonine kinase activity of p-S,3T-CHEK2 [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10652482
displayName	phospho-chek2 [nucleoplasm]
endCoordinate	543
hasModifiedResidue	[ModifiedResidue:10652477] O-phospho-L-threonine at 68 (in Homo sapiens) [ModifiedResidue:10652478] O-phospho-L-serine at 379 (in Homo sapiens) [ModifiedResidue:10652479] O-phospho-L-threonine at 383 (in Homo sapiens) [ModifiedResidue:10652480] O-phospho-L-threonine at 387 (in Homo sapiens)
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-5683784] p-S,3T-CHEK2 [nucleoplasm] - Homo sapiens
maxDepth	1
name	phospho-chek2 p-S,3T-CHEK2 F6TMJ6
producedByEvent	[Reaction:R-XTR-5683792] p-T68-CHEK2 autophosphorylates - Xenopus tropicalis [Reaction:R-XTR-5683792] p-T68-CHEK2 autophosphorylates - Xenopus tropicalis
referenceEntity	[ReferenceGeneProduct:uniprot:F6TMJ6] UniProt:F6TMJ6
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-5683784
startCoordinate	1

(physicalEntity)	[CatalystActivity:10652483] protein serine/threonine kinase activity of p-S,3T-CHEK2 [nucleoplasm]
(output)	[Reaction:R-XTR-5683792] p-T68-CHEK2 autophosphorylates
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-5683784] p-S,3T-CHEK2 [nucleoplasm]

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