Reactome | NOX2 complex:RAC2:GTP [phagocytic vesicle membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10701161] superoxide-generating NAD(P)H oxidase activity of NOX2 complex:RAC2:GTP [phagocytic vesicle membrane]
compartment	[Compartment:1222693] phagocytic vesicle membrane
componentOf	[Complex:R-XTR-9626792] NOX2 complex:S100A8:S100A9:Ca2+ [phagocytic vesicle membrane] - Xenopus tropicalis
consumedByEvent	[Reaction:R-XTR-9626848] S100A8:S100A9:AA:Ca(2+) binds NOX2 complex - Xenopus tropicalis
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10701158
displayName	NOX2 complex:RAC2:GTP [phagocytic vesicle membrane]
hasComponent	[Complex:R-XTR-1996217] NOX2 complex [phagocytic vesicle membrane] [Complex:R-XTR-5668609] RAC2:GTP [phagocytic vesicle membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-9014422] RAC2:GTP:RAC2 phagosome effectors [phagocytic vesicle membrane] - Homo sapiens [Complex:R-HSA-5668618] NOX2 complex:RAC2:GTP [phagocytic vesicle membrane] - Homo sapiens
maxDepth	4
name	NOX2 complex:RAC2:GTP
producedByEvent	[Reaction:R-XTR-9014424] RAC2 binds effectors at the phagocytic vesicle membrane - Xenopus tropicalis [Reaction:R-XTR-5668605] RAC2:GTP binds NOX2 complex - Xenopus tropicalis
schemaClass	Complex
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-5668618
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[Reaction:R-XTR-9014424] RAC2 binds effectors at the phagocytic vesicle membrane [Reaction:R-XTR-5668605] RAC2:GTP binds NOX2 complex
(inferredTo)	[Complex:R-HSA-9014422] RAC2:GTP:RAC2 phagosome effectors [phagocytic vesicle membrane] [Complex:R-HSA-5668618] NOX2 complex:RAC2:GTP [phagocytic vesicle membrane]
(input)	[Reaction:R-XTR-9626848] S100A8:S100A9:AA:Ca(2+) binds NOX2 complex
(hasComponent)	[Complex:R-XTR-9626792] NOX2 complex:S100A8:S100A9:Ca2+ [phagocytic vesicle membrane]
(physicalEntity)	[CatalystActivity:10701161] superoxide-generating NAD(P)H oxidase activity of NOX2 complex:RAC2:GTP [phagocytic vesicle membrane]