Reactome | SERPINA5 binds activated protein C

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SERPINA5 binds activated protein C Show undefined attributes

category	binding
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10698240
displayName	SERPINA5 binds activated protein C
eventOf	[Pathway:R-XTR-9769739] Regulation of clotting cascade - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5591086] SERPINA5 binds activated protein C - Homo sapiens
input	[Complex:R-XTR-141050] Activated protein C [extracellular region] [DefinedSet:R-XTR-5591085-3] Homologues of SERPINA5 [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	SERPINA5 binds activated protein C
output	[Complex:R-XTR-5607007] SERPINA5:Activated protein C [extracellular region]
regulatedBy	[PositiveRegulation:R-HSA-5578890] Positive regulation by 'GAG [plasma membrane]'
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-5591086
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-9769739] Regulation of clotting cascade
(inferredTo)	[Reaction:R-HSA-5591086] SERPINA5 binds activated protein C

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