Reactome | phospho-p-T500,T642,S661-PRKCB [nucleoplasm]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-XTR-5223297] DAG:active PKC:Ca+2 [nuclear envelope] - Xenopus tropicalis
consumedByEvent	[Reaction:R-XTR-5223304] DAG and Ca+2 bind to PKC and tether it to membrane - Xenopus tropicalis
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10696513
displayName	phospho-p-T500,T642,S661-PRKCB [nucleoplasm]
endCoordinate	671
hasModifiedResidue	[ModifiedResidue:10696324] O-phospho-L-threonine at 500 (in Homo sapiens) [ModifiedResidue:10696331] O-phospho-L-serine at 661 (in Homo sapiens) [ModifiedResidue:10696332] O-phospho-L-threonine at 642 (in Homo sapiens)
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-5223294] p-T500,T642,S661-PRKCB [nucleoplasm] - Homo sapiens [DefinedSet:R-HSA-5223295] p-PKCA, p-PKCB [nucleoplasm] - Homo sapiens
maxDepth	1
name	phospho-p-T500,T642,S661-PRKCB A8KBH6
referenceEntity	[ReferenceGeneProduct:uniprot:A8KBH6] UniProt:A8KBH6
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-5223294
startCoordinate	2

(activeUnit)	[CatalystActivity:10696626] calcium,diacylglycerol-dependent serine/threonine kinase activity of DAG:active PKC:Ca+2 [nuclear envelope]
(input)	[Reaction:R-XTR-5223304] DAG and Ca+2 bind to PKC and tether it to membrane
(hasComponent)	[Complex:R-XTR-5223297] DAG:active PKC:Ca+2 [nuclear envelope]
(inferredTo)	[DefinedSet:R-HSA-5223295] p-PKCA, p-PKCB [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-5223294] p-T500,T642,S661-PRKCB [nucleoplasm]

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