Reactome | PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3)

Schema > BlackBoxEvent > Entries

PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3) Show undefined attributes

catalystActivity	[CatalystActivity:10696147] histone methyltransferase activity of CCND1:CDK4:PRMT5:pT5-WDR77:COPRS [nucleoplasm]
category	omitted
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10696278
displayName	PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3)
eventOf	[Pathway:R-XTR-3214858] RMTs methylate histone arginines - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-5216234] PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3) - Homo sapiens
input	2 × [SimpleEntity:R-ALL-77087] AdoMet [nucleoplasm] [CandidateSet:R-XTR-181899] Histone H2A [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3) PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A
output	2 × [SimpleEntity:R-ALL-77502] AdoHcy [nucleoplasm] [CandidateSet:R-XTR-5218310] Me2sR4-histone H2A [nucleoplasm]
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-5216234
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-3214858] RMTs methylate histone arginines
(inferredTo)	[BlackBoxEvent:R-HSA-5216234] PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3)

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