Reactome | LPA-binding receptors bind LPA

Schema > Reaction > Entries

category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10673050
displayName	LPA-binding receptors bind LPA
eventOf	[Pathway:R-XTR-419408] Lysosphingolipid and LPA receptors - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-419389] LPA-binding receptors bind LPA - Homo sapiens
input	[SimpleEntity:R-ALL-417891] LPA [extracellular region] [DefinedSet:R-XTR-419369] LPAR1,2,3,5 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	LPA-binding receptors bind LPA
output	[Complex:R-XTR-419353] LPAR1,2,3,5:LPA [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-419389
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-XTR-419408] Lysosphingolipid and LPA receptors
(inferredTo)	[Reaction:R-HSA-419389] LPA-binding receptors bind LPA

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