Reactome | Iodide is organified

Schema > Reaction > Entries

Iodide is organified Show undefined attributes

catalystActivity	[CatalystActivity:10666955] halogenase activity of p-DUOX1,2:DUOXA1,2:TPO:CAV1:TXNDC11 [plasma membrane]
category	transition
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10668201
displayName	Iodide is organified
eventOf	[Pathway:R-XTR-209968] Thyroxine biosynthesis - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-XTR-209973] Tyrosine is diiodinated - Xenopus tropicalis [Reaction:R-XTR-209815] Tyrosine is monoiodinated - Xenopus tropicalis
inferredFrom	[Reaction:R-HSA-350901] Iodide is organified - Homo sapiens
input	[SimpleEntity:R-ALL-351626] H+ [extracellular region] [SimpleEntity:R-ALL-351629] H2O2 [extracellular region] 2 × [SimpleEntity:R-ALL-209818] I- [extracellular region] [SimpleEntity:R-ALL-351627] NADPH [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	Iodide is organified
output	2 × [SimpleEntity:R-ALL-109276] H2O [extracellular region] [SimpleEntity:R-ALL-351630] I2 [extracellular region] [SimpleEntity:R-ALL-351628] NADP+ [extracellular region]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-350901
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-209968] Thyroxine biosynthesis
(precedingEvent)	[Reaction:R-XTR-209973] Tyrosine is diiodinated [Reaction:R-XTR-209815] Tyrosine is monoiodinated
(inferredTo)	[Reaction:R-HSA-350901] Iodide is organified