Reactome | TLE tetramer [nucleoplasm]

Schema > DefinedSet > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-XTR-3772506] TLE:HDAC1 [nucleoplasm] - Xenopus tropicalis [Complex:R-XTR-8944351] 'canonical' WNT target gene:TCF/LEF:TLE tetramer [nucleoplasm] - Xenopus tropicalis
consumedByEvent	[Reaction:R-XTR-8944349] TLE tetramers bind TCF/LEF at WNT promoters - Xenopus tropicalis
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10693292
displayName	TLE tetramer [nucleoplasm]
hasMember	[Complex:R-XTR-3299557] TLE1 tetramer [nucleoplasm] - Xenopus tropicalis [Complex:R-XTR-3299554] TLE2 tetramer [nucleoplasm] - Xenopus tropicalis [Complex:R-XTR-3299559] TLE4 tetramer [nucleoplasm] - Xenopus tropicalis
inDisease	false
inferredFrom	[DefinedSet:R-HSA-3299565] TLE tetramer [nucleoplasm] - Homo sapiens
maxDepth	3
name	TLE tetramer
producedByEvent	[Reaction:R-XTR-4641229] TLE oligomerizes - Xenopus tropicalis [Reaction:R-XTR-3299569] Beta-catenin displaces TLE:HDAC1 from TCF/LEF - Xenopus tropicalis
schemaClass	DefinedSet
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-3299565

(input)	[Reaction:R-XTR-8944349] TLE tetramers bind TCF/LEF at WNT promoters
(output)	[Reaction:R-XTR-4641229] TLE oligomerizes [Reaction:R-XTR-3299569] Beta-catenin displaces TLE:HDAC1 from TCF/LEF
(hasComponent)	[Complex:R-XTR-8944351] 'canonical' WNT target gene:TCF/LEF:TLE tetramer [nucleoplasm] [Complex:R-XTR-3772506] TLE:HDAC1 [nucleoplasm]
(inferredTo)	[DefinedSet:R-HSA-3299565] TLE tetramer [nucleoplasm]