Reactome | Stimuli-sensing channels

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Stimuli-sensing channels Show undefined attributes

created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10730562
displayName	Stimuli-sensing channels
eventOf	[Pathway:R-XTR-983712] Ion channel transport - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-XTR-8863494] ASICs bind STOML3, (STOM) - Xenopus tropicalis [Reaction:R-XTR-9650165] ASIC trimers bind H+ - Xenopus tropicalis [Reaction:R-XTR-2671885] ASIC trimers:H+ transport extracellular Na+ to cytosol - Xenopus tropicalis [Reaction:R-XTR-2672334] SCNN channels transport extracellular Na+ to cytosol - Xenopus tropicalis [Reaction:R-XTR-2682349] RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels - Xenopus tropicalis [Reaction:R-XTR-2684901] ANOs transport cytosolic Cl- to extracellular region - Xenopus tropicalis [Reaction:R-XTR-9659568] ANO1 transports cytosolic Cl- to extracellular region - Xenopus tropicalis [Reaction:R-XTR-9659611] ANO1 inhibitors bind ANO1 - Xenopus tropicalis [Reaction:R-XTR-2685505] TPCN1/2 transport lysosomal Ca2+ to cytosol - Xenopus tropicalis [Reaction:R-XTR-2744228] CLCN1/2/KA/KB transport cytosolic Cl- to extracellular region - Xenopus tropicalis [Reaction:R-XTR-2730692] CLCN4/5/6 exchange Cl- for H+ - Xenopus tropicalis [Reaction:R-XTR-2730959] CLCN7:OSTM1 exchanges Cl- for H+ - Xenopus tropicalis [Reaction:R-XTR-5333671] CLCAs self cleave - Xenopus tropicalis [Reaction:R-XTR-2744349] TTYH1 transports cytosolic Cl- to extracellular region - Xenopus tropicalis [Reaction:R-XTR-2744242] TTYH2/3 transport cytosolic Cl- to extracellular region - Xenopus tropicalis [Reaction:R-XTR-2744361] BESTs transport cytosolic Cl- to extracellular region - Xenopus tropicalis [Reaction:R-XTR-2752067] BESTs transport cytosolic HCO3- to extracellular region - Xenopus tropicalis [Reaction:R-XTR-2872444] SLC9B1/C2 exchange Na+ for H+ - Xenopus tropicalis [Reaction:R-XTR-2889070] SLC9B2 exchanges Na+ for H+ - Xenopus tropicalis [Pathway:R-XTR-3295583] TRP channels - Xenopus tropicalis
inferredFrom	[Pathway:R-HSA-2672351] Stimuli-sensing channels - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	Stimuli-sensing channels
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-2672351
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-983712] Ion channel transport
(inferredTo)	[Pathway:R-HSA-2672351] Stimuli-sensing channels

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