Reactome | IGF1,2:p-3Y-IGF1R [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-XTR-2404190] IGF1,2:p-3Y-IGF1R:p-3Y-SHC1 [plasma membrane] - Xenopus tropicalis
consumedByEvent	[Reaction:R-XTR-2428930] IGF1,2:p-Y1161,1165,1166-IGF1R binds IRS1,4 - Xenopus tropicalis [Reaction:R-XTR-2428922] IGF1,2:p-Y1161,1165,1166-IGF1R binds IRS2 - Xenopus tropicalis
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10690541
displayName	IGF1,2:p-3Y-IGF1R [plasma membrane]
hasComponent	[DefinedSet:R-XTR-381451] IGF1,2 [extracellular region] [Complex:R-XTR-2404188] p-Y1161,1165,1166-IGF1R [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-2404189] IGF1,2:p-3Y-IGF1R [plasma membrane] - Homo sapiens
maxDepth	3
name	IGF1,2:p-3Y-IGF1R
producedByEvent	[Reaction:R-XTR-2404199] IGF1,2:IGF1R autophosphorylates - Xenopus tropicalis
schemaClass	Complex
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-2404189
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(hasComponent)	[Complex:R-XTR-2404190] IGF1,2:p-3Y-IGF1R:p-3Y-SHC1 [plasma membrane] [Complex:R-XTR-2404185] IGF1,2:p-3Y-IGF1R:SHC1 [plasma membrane] [Complex:R-XTR-2445094] IGF1,2:p-IGF1R:p-IRS1,2,4 [plasma membrane] [Complex:R-XTR-2428921] IGF1,2:p-IGF1R:IRS1,2,4 [plasma membrane] [Complex:R-XTR-2428931] IGF1,2:p-IGF1R:IRS2 [plasma membrane] [Complex:R-XTR-2428923] IGF1,2:p-IGF1R:IRS1,4 [plasma membrane]
(input)	[Reaction:R-XTR-2428922] IGF1,2:p-Y1161,1165,1166-IGF1R binds IRS2 [Reaction:R-XTR-2428930] IGF1,2:p-Y1161,1165,1166-IGF1R binds IRS1,4
(output)	[Reaction:R-XTR-2404199] IGF1,2:IGF1R autophosphorylates
(inferredTo)	[Complex:R-HSA-2404189] IGF1,2:p-3Y-IGF1R [plasma membrane]