Reactome | Synthesis of 15-eicosatetraenoic acid derivatives

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Synthesis of 15-eicosatetraenoic acid derivatives Show undefined attributes

created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10730496
displayName	Synthesis of 15-eicosatetraenoic acid derivatives
eventOf	[Pathway:R-XTR-2142753] Arachidonate metabolism - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:9980] lipoxygenase pathway
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-XTR-2162002] Arachidonate is oxidised to 15S-HpETE by ALOX15/15B - Xenopus tropicalis [Reaction:R-XTR-2161791] 15S-HpETE is reduced to 15S-HETE by GPX1/2/4 - Xenopus tropicalis [Reaction:R-XTR-2161951] Arachidonate is oxidised to 15R-HETE by Acetyl-PTGS2 - Xenopus tropicalis
inferredFrom	[Pathway:R-HSA-2142770] Synthesis of 15-eicosatetraenoic acid derivatives - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Synthesis of 15-eicosatetraenoic acid derivatives
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-2142770
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-2142753] Arachidonate metabolism
(inferredTo)	[Pathway:R-HSA-2142770] Synthesis of 15-eicosatetraenoic acid derivatives

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