Reactome | Dimerization of Tie2/Ang1 complex

Schema > Reaction > Entries

category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10667199
displayName	Dimerization of Tie2/Ang1 complex
eventOf	[Pathway:R-XTR-210993] Tie2 Signaling - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-210881] Dimerization of Tie2/Ang1 complex - Homo sapiens
input	2 × [Complex:R-XTR-204807] ANGPT1:TEK [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Dimerization of Tie2/Ang1 complex
output	[Complex:R-XTR-210862] 2xANGPT1:TEK [plasma membrane]
precedingEvent	[Reaction:R-XTR-204779] Interaction of Tie2 with Ang1 - Xenopus tropicalis
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-210881
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-XTR-210993] Tie2 Signaling
(inferredTo)	[Reaction:R-HSA-210881] Dimerization of Tie2/Ang1 complex

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