Reactome | SKI complexes with the Smad complex, suppressing BMP2 signalling

Schema > Reaction > Entries

SKI complexes with the Smad complex, suppressing BMP2 signalling Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10665379
displayName	SKI complexes with the Smad complex, suppressing BMP2 signalling
eventOf	[Pathway:R-XTR-201451] Signaling by BMP - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:23767] negative regulation of BMP signaling pathway
inferredFrom	[Reaction:R-HSA-201423] SKI complexes with the Smad complex, suppressing BMP2 signalling - Homo sapiens
input	[Complex:R-XTR-201450] p-2S-SMAD1/5/8:SMAD4 [nucleoplasm] [EntityWithAccessionedSequence:R-XTR-173473] ski [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	SKI complexes with the Smad complex, suppressing BMP2 signalling
output	[Complex:R-XTR-201427] p-2S-SMAD1/5/8:SMAD4:SKI [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-201423
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-201451] Signaling by BMP
(inferredTo)	[Reaction:R-HSA-201423] SKI complexes with the Smad complex, suppressing BMP2 signalling

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