Reactome | creatine + ATP => phosphocreatine + ADP [CK octamer]

Schema > Reaction > Entries

creatine + ATP => phosphocreatine + ADP [CK octamer] Show undefined attributes

catalystActivity	[CatalystActivity:10665228] creatine kinase activity of CK octamers [mitochondrial inner membrane]
category	transition
compartment	[Compartment:70616] mitochondrial inner membrane [Compartment:70101] cytosol
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10665230
displayName	creatine + ATP => phosphocreatine + ADP [CK octamer]
eventOf	[Pathway:R-XTR-71288] Creatine metabolism - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-200326] creatine + ATP => phosphocreatine + ADP [CK octamer] - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [SimpleEntity:R-ALL-29916] CRET [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	creatine + ATP => phosphocreatine + ADP [CK octamer] creatine + ATP => N-phosphocreatine + ADP + H(+)
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-200351] Pcr [cytosol]
precedingEvent	[Reaction:R-XTR-71286] guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine - Xenopus tropicalis [Reaction:R-XTR-200396] Creatine transport across the plasma membrane - Xenopus tropicalis
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-200326
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-71288] Creatine metabolism
(inferredTo)	[Reaction:R-HSA-200326] creatine + ATP => phosphocreatine + ADP [CK octamer]

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