Reactome | Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell

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Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Show undefined attributes

created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10729512
displayName	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
eventOf	[Pathway:R-XTR-1280218] Adaptive Immune System - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:159969] regulation of immune response
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-XTR-9679740] ITGA4:ITGB1 binds natalizumab - Xenopus tropicalis [Reaction:R-XTR-199032] MADCAM1-1 binds Integrin alpha4beta7 - Xenopus tropicalis [Reaction:R-XTR-199154] CD200 binds to CD200R - Xenopus tropicalis [Reaction:R-XTR-199404] CD40L binds CD40 - Xenopus tropicalis [Reaction:R-XTR-5685607] Sialic acid binds SIGLEC - Xenopus tropicalis [Reaction:R-XTR-5685604] SLAMF6 binds SLAMF6 - Xenopus tropicalis [Reaction:R-XTR-5685605] SLAMF7 binds SLAMF7 - Xenopus tropicalis [Reaction:R-XTR-5686625] LAIR1 binds collagen - Xenopus tropicalis [Reaction:R-XTR-5696358] TREM,CD300 binds lipids - Xenopus tropicalis
inferredFrom	[Pathway:R-HSA-198933] Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-198933
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-1280218] Adaptive Immune System
(inferredTo)	[Pathway:R-HSA-198933] Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell

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