Reactome | Transport of fringe-modified NOTCH to plasma membrane

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Transport of fringe-modified NOTCH to plasma membrane Show undefined attributes

category	omitted
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10685995
displayName	Transport of fringe-modified NOTCH to plasma membrane
eventOf	[Pathway:R-XTR-1912420] Pre-NOTCH Processing in Golgi - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-1912379] Transport of fringe-modified NOTCH to plasma membrane - Homo sapiens
input	[CandidateSet:R-XTR-1911547] FRINGE-modified NOTCH [Golgi membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Transport of fringe-modified NOTCH to plasma membrane
output	[CandidateSet:R-XTR-1911550] Fringe-modified NOTCH [plasma membrane]
precedingEvent	[Reaction:R-XTR-1912372] Fringe-modified Pre-NOTCH is cleaved by FURIN - Xenopus tropicalis
regulatedBy	[NegativeRegulation:10685996] Negative regulation by 'TMED2 [endoplasmic reticulum-Golgi intermediate compartment membrane]'
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-1912379
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-1912420] Pre-NOTCH Processing in Golgi
(inferredTo)	[BlackBoxEvent:R-HSA-1912379] Transport of fringe-modified NOTCH to plasma membrane

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