Reactome | Shelterin complex [nucleoplasm]

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Shelterin complex [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-XTR-9671076] Telomeric G-strand chromosome end:Shelterin [nucleoplasm] - Xenopus tropicalis [Complex:R-XTR-9629214] AP-Telomeric DNA:Shelterin [nucleoplasm] - Xenopus tropicalis [Complex:R-XTR-174454] RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] - Xenopus tropicalis
consumedByEvent	[BlackBoxEvent:R-XTR-176700] Incorporation Of Extended And Processed Telomere End Into Higher Order T-Loop And Associated Protein Structure - Xenopus tropicalis [Reaction:R-XTR-181450] Incorporation Of Extended And Processed Telomere End Into Associated Protein Structure - Xenopus tropicalis
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10660200
displayName	Shelterin complex [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-XTR-174889] acd [nucleoplasm] [EntityWithAccessionedSequence:R-XTR-174890] pot1 [nucleoplasm] [Complex:R-XTR-9671130] TERF1 homodimer [nucleoplasm] [Complex:R-XTR-9671119] TERF2 homodimer [nucleoplasm] 2 × [EntityWithAccessionedSequence:R-XTR-174873] terf2ip [nucleoplasm] [EntityWithAccessionedSequence:R-XTR-174883] tinf2 [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-174898] Shelterin complex [nucleoplasm] - Homo sapiens
maxDepth	3
name	Shelterin complex
producedByEvent	[BlackBoxEvent:R-XTR-3785711] Telomere shortening during replicative exhaustion - Xenopus tropicalis
schemaClass	Complex
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-174898
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(hasComponent)	[Complex:R-XTR-9629214] AP-Telomeric DNA:Shelterin [nucleoplasm] [Complex:R-XTR-9629187] Gh-Telomeric DNA:Shelterin [nucleoplasm] [Complex:R-XTR-9671076] Telomeric G-strand chromosome end:Shelterin [nucleoplasm] [Complex:R-XTR-164683] Telomerase RNP Bound and base-paired to the Telomeric Chromosome End [nucleoplasm] [Complex:R-XTR-163098] Telomerase RNP:Telomeric Chromosome End with an Additional single Stranded Telomere repeat [nucleoplasm] [Complex:R-XTR-164619] Telomerase Holoenzyme:Telomeric RNP End with Two Additional Single Stranded Telomere Repeats [nucleoplasm] [Complex:R-XTR-9671097] Telomeric G-strand chromosome end with two additional single strand repeats [nucleoplasm] [Complex:R-XTR-174454] RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end [nucleoplasm] [Complex:R-XTR-176703] Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex [nucleoplasm] [Complex:R-XTR-9690022] Extended And Processed Telomere End [nucleoplasm] [Complex:R-XTR-182751] Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm]
(output)	[BlackBoxEvent:R-XTR-3785711] Telomere shortening during replicative exhaustion
(input)	[BlackBoxEvent:R-XTR-176700] Incorporation Of Extended And Processed Telomere End Into Higher Order T-Loop And Associated Protein Structure [Reaction:R-XTR-181450] Incorporation Of Extended And Processed Telomere End Into Associated Protein Structure
(inferredTo)	[Complex:R-HSA-174898] Shelterin complex [nucleoplasm]

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