Reactome | Phosphorylation of Cdh1 by Cyclin A:Cdk2

Schema > Reaction > Entries

Phosphorylation of Cdh1 by Cyclin A:Cdk2 Show undefined attributes

catalystActivity	[CatalystActivity:10661834] cyclin-dependent protein serine/threonine kinase activity of Cyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complex [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10661836
displayName	Phosphorylation of Cdh1 by Cyclin A:Cdk2
eventOf	[Pathway:R-XTR-176408] Regulation of APC/C activators between G1/S and early anaphase - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-XTR-174139] Dissociation of phospho-Cdh1 from the APC/C complex - Xenopus tropicalis [Reaction:R-XTR-174124] Dephosphorylation of phospho-Cdh1 - Xenopus tropicalis
inferredFrom	[Reaction:R-HSA-174079] Phosphorylation of Cdh1 by Cyclin A:Cdk2 - Homo sapiens
input	[SimpleEntity:R-ALL-29358] ATP [nucleoplasm] [Complex:R-XTR-188374] Cyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complex [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Phosphorylation of Cdh1 by Cyclin A:Cdk2
output	[SimpleEntity:R-ALL-113582] ADP [nucleoplasm] [Complex:R-XTR-188387] Cyclin A:phospho-Cdk2(Thr 160):phospho-Cdh1:phospho-APC/C complex [nucleoplasm]
precedingEvent	[Reaction:R-XTR-188371] Association of Cyclin A:Cdk2 with Cdh1 - Xenopus tropicalis
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-174079
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-176408] Regulation of APC/C activators between G1/S and early anaphase
(precedingEvent)	[Reaction:R-XTR-174139] Dissociation of phospho-Cdh1 from the APC/C complex [Reaction:R-XTR-174124] Dephosphorylation of phospho-Cdh1
(inferredTo)	[Reaction:R-HSA-174079] Phosphorylation of Cdh1 by Cyclin A:Cdk2