Reactome | Nuclear Pore Complex (NPC) [nuclear envelope]

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Nuclear Pore Complex (NPC) [nuclear envelope] Show undefined attributes

catalystActivities	[CatalystActivity:10692313] SUMO transferase activity of Nuclear Pore Complex (NPC) [nuclear envelope] [CatalystActivity:10661507] structural constituent of nuclear pore activity of Nuclear Pore Complex (NPC) [nuclear envelope] [CatalystActivity:10685284] narrow pore channel activity of Nuclear Pore Complex (NPC) [nuclear envelope]
compartment	[Compartment:13231] nuclear envelope
componentOf	[Complex:R-XTR-113815] NPC:NXF1,2:NXT1:EJC:CBC:mRNA [nucleoplasm] - Xenopus tropicalis
consumedByEvent	[Reaction:R-XTR-2990882] CDK1 phosphorylates NUP98 - Xenopus tropicalis
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10655826
displayName	Nuclear Pore Complex (NPC) [nuclear envelope]
hasComponent	8 × [EntityWithAccessionedSequence:R-XTR-157738] aaas [nuclear envelope] 16 × [GenomeEncodedEntity:R-XTR-157722] Ghost homologue of NUP210 [nuclear envelope] 16 × [GenomeEncodedEntity:R-XTR-6805169] Ghost homologue of POM121 [nuclear envelope] 32 × [EntityWithAccessionedSequence:R-XTR-6805183] ndc1 [nuclear envelope] 32 × [Complex:R-XTR-377883] Nup107-160 complex [cytosol] 8 × [EntityWithAccessionedSequence:R-XTR-157695] nup153 [nucleoplasm] 16 × [EntityWithAccessionedSequence:R-XTR-157752] nup188 [nuclear envelope] 8 × [EntityWithAccessionedSequence:R-XTR-157691] nup214 [cytosol] 16 × [EntityWithAccessionedSequence:R-XTR-157697] nup42 [cytosol] 32 × [EntityWithAccessionedSequence:R-XTR-157740] nup50 [nucleoplasm] 32 × [Complex:R-XTR-157712] Nup62 Complex [nuclear envelope] 32 × [EntityWithAccessionedSequence:R-XTR-157753] nup88 [cytosol] 32 × [Complex:R-XTR-9634183] Nup93 complex [nuclear envelope] 8 × [EntityWithAccessionedSequence:R-XTR-2990912] nup98 [nuclear envelope] 48 × [EntityWithAccessionedSequence:R-XTR-157718] rae1 [nuclear envelope] 8 × [EntityWithAccessionedSequence:R-XTR-157703] ranbp2 [cytosol] 16 × [EntityWithAccessionedSequence:R-XTR-157750] seh1l [nuclear envelope] 16 × [EntityWithAccessionedSequence:R-XTR-157692] tpr [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-157689] Nuclear Pore Complex (NPC) [nuclear envelope] - Homo sapiens
isRequired	[Requirement:10655913] Requirement by 'Nuclear Pore Complex (NPC) [nuclear envelope]'
maxDepth	3
name	Nuclear Pore Complex (NPC)
positivelyRegulates	[Requirement:10655913] Requirement by 'Nuclear Pore Complex (NPC) [nuclear envelope]'
schemaClass	Complex
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-157689
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(physicalEntity)	[CatalystActivity:10692313] SUMO transferase activity of Nuclear Pore Complex (NPC) [nuclear envelope] [CatalystActivity:10661507] structural constituent of nuclear pore activity of Nuclear Pore Complex (NPC) [nuclear envelope] [CatalystActivity:10685284] narrow pore channel activity of Nuclear Pore Complex (NPC) [nuclear envelope]
(input)	[Reaction:R-XTR-2990882] CDK1 phosphorylates NUP98
(regulator)	[Requirement:10655913] Requirement by 'Nuclear Pore Complex (NPC) [nuclear envelope]'
(hasComponent)	[Complex:R-XTR-113815] NPC:NXF1,2:NXT1:EJC:CBC:mRNA [nucleoplasm] [Complex:R-XTR-159259] NPC:NXF1:NXT1:EJC:CBC:mRNA [cytosol]
(inferredTo)	[Complex:R-HSA-157689] Nuclear Pore Complex (NPC) [nuclear envelope]

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