Reactome | Activin A,AB,B:ACVR2A,B:ACVR1B [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10680941] protein serine/threonine kinase activity of Activin A,AB,B:ACVR2A,B:ACVR1B [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-XTR-1181149] ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin - Xenopus tropicalis
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10680930
displayName	Activin A,AB,B:ACVR2A,B:ACVR1B [plasma membrane]
hasComponent	[DefinedSet:R-XTR-2470494] Activin A,AB,B [extracellular region] 2 × [EntityWithAccessionedSequence:R-XTR-205867] ACVR1B [plasma membrane] 2 × [DefinedSet:R-XTR-1181136] ACVR2A,B [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-1549493] Activin A,AB,B:ACVR2A,B:ACVR1B [plasma membrane] - Homo sapiens
maxDepth	4
name	Activin A,AB,B:ACVR2A,B:ACVR1B
producedByEvent	[Reaction:R-XTR-1181153] Activin A,AB,B binds Activin Receptor ACVR2A,B:ACVR1B - Xenopus tropicalis
schemaClass	Complex
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-1549493
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-XTR-1181149] ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin
(physicalEntity)	[CatalystActivity:10680941] protein serine/threonine kinase activity of Activin A,AB,B:ACVR2A,B:ACVR1B [plasma membrane]
(output)	[Reaction:R-XTR-1181153] Activin A,AB,B binds Activin Receptor ACVR2A,B:ACVR1B
(inferredTo)	[Complex:R-HSA-1549493] Activin A,AB,B:ACVR2A,B:ACVR1B [plasma membrane]

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