Reactome | Dephosphorylation of p130 (RBL2) by PP2A

Schema > Reaction > Entries

Dephosphorylation of p130 (RBL2) by PP2A Show undefined attributes

catalystActivity	[CatalystActivity:10682222] phosphoprotein phosphatase activity of PP2A [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10682226
displayName	Dephosphorylation of p130 (RBL2) by PP2A
eventOf	[Pathway:R-XTR-69231] Cyclin D associated events in G1 - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-1363276] Dephosphorylation of p130 (RBL2) by PP2A - Homo sapiens
input	3 × [SimpleEntity:R-ALL-113518] H2O [nucleoplasm] [EntityWithAccessionedSequence:R-XTR-1226084] phospho-rbl2 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Dephosphorylation of p130 (RBL2) by PP2A Dephosphorylation of p107 by PP2A
output	3 × [SimpleEntity:R-ALL-113550] Pi [nucleoplasm] [EntityWithAccessionedSequence:R-XTR-389102] rbl2 [nucleoplasm]
precedingEvent	[Reaction:R-XTR-1226094] Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex - Xenopus tropicalis
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-1363276
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-69231] Cyclin D associated events in G1
(inferredTo)	[Reaction:R-HSA-1363276] Dephosphorylation of p130 (RBL2) by PP2A

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