Reactome | CRAT transfers ISB to CAR

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CRAT transfers ISB to CAR Show undefined attributes

catalystActivity	[CatalystActivity:10555503] carnitine O-acyltransferase activity of CRAT [mitochondrial inner membrane]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10555505
displayName	CRAT transfers ISB to CAR
eventOf	[Pathway:R-SSC-70895] Branched-chain amino acid catabolism - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9971123] CRAT transfers ISB to CAR - Homo sapiens
input	[SimpleEntity:R-ALL-201023] CAR [mitochondrial matrix] [SimpleEntity:R-ALL-70851] ISB-CoA [mitochondrial matrix]
isInDisease	false
isInferred	true
maxDepth	1
name	CRAT transfers ISB to CAR 2-methylpropanoyl-CoA + (R)-carnitine => O-isobutanoyl-(R)-carnitine + CoA
output	[SimpleEntity:R-ALL-29374] CoA-SH [mitochondrial matrix] [SimpleEntity:R-ALL-9971124] ISB-CAR [mitochondrial matrix]
precedingEvent	[Reaction:R-SSC-9859163] DBT transfers BCAA to CoA - Sus scrofa
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-9971123
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-70895] Branched-chain amino acid catabolism
(inferredTo)	[Reaction:R-HSA-9971123] CRAT transfers ISB to CAR

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