Reactome | TIMM21 carries COX4, COX5A, COX6C to MT-CO1:MITRAC

Schema > Reaction > Entries

TIMM21 carries COX4, COX5A, COX6C to MT-CO1:MITRAC Show undefined attributes

category	binding
compartment	[Compartment:70616] mitochondrial inner membrane [Compartment:17927] mitochondrial intermembrane space
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10553004
displayName	TIMM21 carries COX4, COX5A, COX6C to MT-CO1:MITRAC
eventOf	[Pathway:R-SSC-9864848] Complex IV assembly - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-9865449] Metallochaperone inserts Cu2+ into MT-CO1 - Sus scrofa
goBiologicalProcess	[GO_BiologicalProcess:18876] protein insertion into mitochondrial inner membrane
inferredFrom	[Reaction:R-HSA-9865412] TIMM21 carries COX4, COX5A, COX6C to MT-CO1:MITRAC - Homo sapiens
input	[Complex:R-SSC-9865433] MT-CO1:Mg2+:PE:CL:MITRAC [mitochondrial inner membrane] [Complex:R-SSC-9865418] TIMM21:COX4:COX5A:COX6C [mitochondrial intermembrane space]
isInDisease	false
isInferred	true
maxDepth	1
name	TIMM21 carries COX4, COX5A, COX6C to MT-CO1:MITRAC
output	[Complex:R-SSC-9865410] MT-CO1:Mg2+:PE:CL:MITRAC:TIMM21:COX4:COX5A:COX6C [mitochondrial inner membrane]
precedingEvent	[BlackBoxEvent:R-SSC-9865350] Nascent MT-CO1 binds to MITRAC, Mg2+, PE, CL - Sus scrofa
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-9865412
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-9864848] Complex IV assembly
(inferredTo)	[Reaction:R-HSA-9865412] TIMM21 carries COX4, COX5A, COX6C to MT-CO1:MITRAC
(precedingEvent)	[Reaction:R-SSC-9865449] Metallochaperone inserts Cu2+ into MT-CO1

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