Reactome | prekallikrein + kininogen -> prekallikrein:kininogen

Schema > Reaction > Entries

prekallikrein + kininogen -> prekallikrein:kininogen Show undefined attributes

category	binding
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10552603
displayName	prekallikrein + kininogen -> prekallikrein:kininogen
eventOf	[Pathway:R-SSC-9970672] FXIIa activates plasma kallikrein-kinin system - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-9857952] prekallikrein:kininogen binds cell surface receptors - Sus scrofa
inferredFrom	[Reaction:R-HSA-9857939] prekallikrein + kininogen -> prekallikrein:kininogen - Homo sapiens
input	[EntityWithAccessionedSequence:R-SSC-9857965] KLKB1 [extracellular region] [EntityWithAccessionedSequence:R-SSC-158125] KNG1 [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	prekallikrein + kininogen -> prekallikrein:kininogen KLKB1(20-638) + KNG1(19-644) -> KLKB1(20-638):KNG1(19-644)
output	[Complex:R-SSC-9857934] KLKB1(20-638):KNG1(19-644) [extracellular region]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-9857939
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-9970672] FXIIa activates plasma kallikrein-kinin system
(precedingEvent)	[Reaction:R-SSC-9857952] prekallikrein:kininogen binds cell surface receptors
(inferredTo)	[Reaction:R-HSA-9857939] prekallikrein + kininogen -> prekallikrein:kininogen

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