Reactome | p-S225-SPHK1 localizes to cytosol

Schema > BlackBoxEvent > Entries

category	omitted
compartment	[Compartment:70101] cytosol [Compartment:7660] nucleoplasm
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10551260
displayName	p-S225-SPHK1 localizes to cytosol
eventOf	[Pathway:R-SSC-9833482] PKR-mediated signaling - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-9836621] p-S225-SPHK1 localizes to cytosol - Homo sapiens
input	[EntityWithAccessionedSequence:R-SSC-9836613] phospho-SPHK1 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	p-S225-SPHK1 localizes to cytosol
output	[EntityWithAccessionedSequence:R-SSC-5218716] phospho-SPHK1 [cytosol]
precedingEvent	[Reaction:R-SSC-9836617] p-PKR dimer phosphorylates SPHK1 - Sus scrofa
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:49633] Sus scrofa
stId	R-SSC-9836621
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SSC-9833482] PKR-mediated signaling
(inferredTo)	[BlackBoxEvent:R-HSA-9836621] p-S225-SPHK1 localizes to cytosol

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