Reactome | PDCD1 binds PDCD1 inhibitors

Schema > Reaction > Entries

category	binding
compartment	[Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10547025
displayName	PDCD1 binds PDCD1 inhibitors
eventOf	[Pathway:R-SSC-389948] Co-inhibition by PD-1 - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9679421] PDCD1 binds PDCD1 inhibitors - Homo sapiens
input	[EntityWithAccessionedSequence:R-SSC-197604] PDCD1 [plasma membrane] [DefinedSet:R-ALL-9679406] PDCD1 inhibitors [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	PDCD1 binds PDCD1 inhibitors
output	[Complex:R-SSC-9679420] PDCD1:PDCD1 inhibitors [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-9679421
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SSC-389948] Co-inhibition by PD-1
(inferredTo)	[Reaction:R-HSA-9679421] PDCD1 binds PDCD1 inhibitors

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