Reactome | ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63-linked pUb-TRAF6 oligomer [cytosol]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10546194] ubiquitin-protein transferase activity of ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63-linked pUb-TRAF6 oligomer [cytosol]
compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-SSC-9645449] ALPK1:ADP-heptose:p-T9-TIFA:polyUb-TRAF6:p-T184,T187-TAK1:TAB1:TAB2/TAB3: free polyUb chain [cytosol] - Sus scrofa
consumedByEvent	[Reaction:R-SSC-9645406] ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63pUb-TRAF6 oligomer recruits MAP3K7 (TAK1) - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10546193
displayName	ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63-linked pUb-TRAF6 oligomer [cytosol]
hasComponent	[Complex:R-SSC-9645404] ALPK1:ADP-heptose:p-T9-TIFA oligomer [cytosol] 3 × [EntityWithAccessionedSequence:R-SSC-2685681] TRAF6 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-9645508] ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63-linked pUb-TRAF6 oligomer [cytosol] - Homo sapiens
maxDepth	4
name	ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63-linked pUb-TRAF6 oligomer
producedByEvent	[BlackBoxEvent:R-SSC-9645414] Auto ubiquitination of TRAF6 bound to ALPK1:ADP-heptose:TIFA oligomer - Sus scrofa
schemaClass	Complex
species	[Species:49633] Sus scrofa
stId	R-SSC-9645508
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-SSC-9645406] ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63pUb-TRAF6 oligomer recruits MAP3K7 (TAK1)
(physicalEntity)	[CatalystActivity:10546194] ubiquitin-protein transferase activity of ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63-linked pUb-TRAF6 oligomer [cytosol]
(output)	[BlackBoxEvent:R-SSC-9645414] Auto ubiquitination of TRAF6 bound to ALPK1:ADP-heptose:TIFA oligomer
(hasComponent)	[Complex:R-SSC-9645449] ALPK1:ADP-heptose:p-T9-TIFA:polyUb-TRAF6:p-T184,T187-TAK1:TAB1:TAB2/TAB3: free polyUb chain [cytosol] [Complex:R-SSC-9645445] ALPK1:ADP-heptose:p-T9-TIFA:polyUb-TRAF6:TAK1:TAB1:TAB2/TAB3: free polyUb chain [cytosol]
(inferredTo)	[Complex:R-HSA-9645508] ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63-linked pUb-TRAF6 oligomer [cytosol]

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