Reactome | PRKCZ autophosphorylates downstream of estrogen stimulation

Schema > Reaction > Entries

PRKCZ autophosphorylates downstream of estrogen stimulation Show undefined attributes

catalystActivity	[CatalystActivity:10545827] protein serine/threonine kinase activity of PDPK1:PIP3:p-T410-PRKCZ [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10545829
displayName	PRKCZ autophosphorylates downstream of estrogen stimulation
eventOf	[Pathway:R-SSC-9634635] Estrogen-stimulated signaling through PRKCZ - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-9632906] PRKCZ recruits RAS in response to estrogen stimulation - Sus scrofa
inferredFrom	[Reaction:R-HSA-9632858] PRKCZ autophosphorylates downstream of estrogen stimulation - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-SSC-437184] PDPK1:PIP3:p-T410-PRKCZ [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	PRKCZ autophosphorylates downstream of estrogen stimulation
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-SSC-9632853] PDPK1:PIP3:pS, p-T410 PRKCZ [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-9632858
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-9634635] Estrogen-stimulated signaling through PRKCZ
(precedingEvent)	[Reaction:R-SSC-9632906] PRKCZ recruits RAS in response to estrogen stimulation
(inferredTo)	[Reaction:R-HSA-9632858] PRKCZ autophosphorylates downstream of estrogen stimulation

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