Reactome | Dimerization of p-IRF7

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10484525
displayName	Dimerization of p-IRF7
eventOf	[Pathway:R-SSC-975110] TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-9604487] p-IRF7:p-IRF7 translocates to the nucleus - Sus scrofa [Reaction:R-SSC-933531] Translocation of p-IRF7:p-IRF7 to nucleus - Sus scrofa
inferredFrom	[Reaction:R-HSA-933533] Dimerization of p-IRF7 - Homo sapiens
input	2 × [EntityWithAccessionedSequence:R-SSC-450318] phospho-Irf7 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Dimerization of p-IRF7
output	[Complex:R-SSC-450344] p-2S-IRF7:p-2S-IRF7 [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-933533
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SSC-975110] TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling [Pathway:R-SSC-933541] TRAF6 mediated IRF7 activation
(precedingEvent)	[Reaction:R-SSC-9604487] p-IRF7:p-IRF7 translocates to the nucleus [Reaction:R-SSC-933531] Translocation of p-IRF7:p-IRF7 to nucleus
(inferredTo)	[Reaction:R-HSA-933533] Dimerization of p-IRF7