Reactome | NGF-stimulated transcription

Schema > Pathway > Entries

created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10558843
displayName	NGF-stimulated transcription
eventOf	[Pathway:R-SSC-198725] Nuclear Events (kinase and transcription factor activation) - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-SSC-9612501] SGK phosphorylates CREB1 - Sus scrofa [Reaction:R-SSC-9612509] SGK phosphorylates SRF - Sus scrofa [Reaction:R-SSC-9613213] NAB2 and CHD4 bind and repress EGR-mediated RRAD gene expression - Sus scrofa
inferredFrom	[Pathway:R-HSA-9031628] NGF-stimulated transcription - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	NGF-stimulated transcription
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49633] Sus scrofa
stId	R-SSC-9031628
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SSC-198725] Nuclear Events (kinase and transcription factor activation)
(inferredTo)	[Pathway:R-HSA-9031628] NGF-stimulated transcription

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