Reactome | STUB1 polyubiquitinates RUNX2

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STUB1 polyubiquitinates RUNX2 Show undefined attributes

catalystActivity	[CatalystActivity:10543028] ubiquitin protein ligase activity of RUNX2:STUB1 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10543030
displayName	STUB1 polyubiquitinates RUNX2
eventOf	[Pathway:R-SSC-8939902] Regulation of RUNX2 expression and activity - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9009308] STUB1 polyubiquitinates RUNX2 - Homo sapiens
input	[Complex:R-SSC-9009311] RUNX2:STUB1 [cytosol] 3 × [DefinedSet:R-SSC-113595] Ub [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	STUB1 polyubiquitinates RUNX2
output	[EntityWithAccessionedSequence:R-SSC-9008082] RUNX2 [cytosol] [EntityWithAccessionedSequence:R-SSC-975970] STUB1 [cytosol]
precedingEvent	[Reaction:R-SSC-9009309] RUNX2 binds STUB1 - Sus scrofa
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-9009308
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-8939902] Regulation of RUNX2 expression and activity
(inferredTo)	[Reaction:R-HSA-9009308] STUB1 polyubiquitinates RUNX2

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