Reactome | TPST1,2 transfer SO4(2-) from PAPS to PODXL2

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TPST1,2 transfer SO4(2-) from PAPS to PODXL2 Show undefined attributes

catalystActivity	[CatalystActivity:10541459] protein-tyrosine sulfotransferase activity of TPST1,2 [Golgi membrane]
category	transition
compartment	[Compartment:17963] Golgi lumen [Compartment:20699] Golgi membrane
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10541461
displayName	TPST1,2 transfer SO4(2-) from PAPS to PODXL2
eventOf	[Pathway:R-SSC-156584] Cytosolic sulfonation of small molecules - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-8953499] IMPAD1 hydrolyses PAP to AMP - Sus scrofa
inferredFrom	[Reaction:R-HSA-8954262] TPST1,2 transfer SO4(2-) from PAPS to PODXL2 - Homo sapiens
input	2 × [SimpleEntity:R-ALL-741440] PAPS [Golgi lumen] [EntityWithAccessionedSequence:R-SSC-8954248] PODXL2 [Golgi lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	TPST1,2 transfer SO4(2-) from PAPS to PODXL2
output	2 × [SimpleEntity:R-ALL-742343] PAP [Golgi lumen] [EntityWithAccessionedSequence:R-SSC-8954273] PODXL2 [Golgi lumen]
precedingEvent	[Reaction:R-SSC-741449] SLC35B2,3 exchange cytosolic PAPS with Golgi PAP - Sus scrofa
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-8954262
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-156584] Cytosolic sulfonation of small molecules
(precedingEvent)	[Reaction:R-SSC-8953499] IMPAD1 hydrolyses PAP to AMP
(inferredTo)	[Reaction:R-HSA-8954262] TPST1,2 transfer SO4(2-) from PAPS to PODXL2

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