Reactome | IL12B:IL23A translocates from ER lumen to extracellular space

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IL12B:IL23A translocates from ER lumen to extracellular space Show undefined attributes

category	omitted
compartment	[Compartment:984] extracellular region [Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10540199
displayName	IL12B:IL23A translocates from ER lumen to extracellular space
eventOf	[Pathway:R-SSC-9020933] Interleukin-23 signaling - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-SSC-447130] Interleukin-23 binds interleukin-23 receptor - Sus scrofa
inferredFrom	[BlackBoxEvent:R-HSA-8950741] IL12B:IL23A translocates from ER lumen to extracellular space - Homo sapiens
input	[Complex:R-SSC-8950275] IL12B:IL23A [endoplasmic reticulum lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	IL12B:IL23A translocates from ER lumen to extracellular space Interleukin-23 traslocates to the extracellular space IL23A:IL12B complex is traslocated to the extracellular space Interleukin-23A:Interleukin-12B complex is traslocated to the extracellular space
output	[Complex:R-SSC-447217] IL12B:IL23A [extracellular region]
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:49633] Sus scrofa
stId	R-SSC-8950741
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-9020933] Interleukin-23 signaling
(precedingEvent)	[BlackBoxEvent:R-SSC-447130] Interleukin-23 binds interleukin-23 receptor
(inferredTo)	[BlackBoxEvent:R-HSA-8950741] IL12B:IL23A translocates from ER lumen to extracellular space

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