Reactome | MCU translocates calcium from the mitochondrial intermembrane space to the mitochondrial matrix

Schema > Reaction > Entries

MCU translocates calcium from the mitochondrial intermembrane space to the mitochondrial matrix Show undefined attributes

catalystActivity	[CatalystActivity:10539933] calcium channel activity of MCU complex [mitochondrial inner membrane]
category	transition
compartment	[Compartment:70616] mitochondrial inner membrane
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10539935
displayName	MCU translocates calcium from the mitochondrial intermembrane space to the mitochondrial matrix
eventOf	[Pathway:R-SSC-8949215] Mitochondrial calcium ion transport - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8949178] MCU translocates calcium from the mitochondrial intermembrane space to the mitochondrial matrix - Homo sapiens
input	[SimpleEntity:R-ALL-8949232] Ca2+ [mitochondrial intermembrane space]
isInDisease	false
isInferred	true
maxDepth	1
name	MCU translocates calcium from the mitochondrial intermembrane space to the mitochondrial matrix
output	[SimpleEntity:R-ALL-8949220] Ca2+ [mitochondrial matrix]
precedingEvent	[Reaction:R-SSC-8949649] PMPCA:PMPCB cleaves the transit peptide of proSMDT1 (proEMRE) - Sus scrofa
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-8949178
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-8949215] Mitochondrial calcium ion transport
(inferredTo)	[Reaction:R-HSA-8949178] MCU translocates calcium from the mitochondrial intermembrane space to the mitochondrial matrix

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