Reactome | TRIM27 binds PTEN

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10533560
displayName	TRIM27 binds PTEN
eventOf	[Pathway:R-SSC-8948751] Regulation of PTEN stability and activity - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-8851011] TRIM27 polyubiquitinates PTEN - Sus scrofa
inferredFrom	[Reaction:R-HSA-8850997] TRIM27 binds PTEN - Homo sapiens
input	[EntityWithAccessionedSequence:R-SSC-199420] PTEN [cytosol] [EntityWithAccessionedSequence:R-SSC-8851002] TRIM27 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	TRIM27 binds PTEN
output	[Complex:R-SSC-8851000] PTEN:TRIM27 [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-8850997
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SSC-8948751] Regulation of PTEN stability and activity
(precedingEvent)	[Reaction:R-SSC-8851011] TRIM27 polyubiquitinates PTEN
(inferredTo)	[Reaction:R-HSA-8850997] TRIM27 binds PTEN

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