Reactome | PTK6 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-SSC-8857567] HBEGF:EGFR:p-Y525-GPNMB:LINC01139:PTK6:LRRK2 [plasma membrane] - Sus scrofa
consumedByEvent	[Reaction:R-SSC-8847995] Activated ERBB2 binds PTK6 (BRK) - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10532728
displayName	PTK6 [cytosol]
endCoordinate	451
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-8848000] PTK6 [cytosol] - Homo sapiens
maxDepth	1
name	PTK6 A0A286ZYS4
producedByEvent	[Reaction:R-SSC-8849435] PTPN1 dephosphorylates PTK6 - Sus scrofa
referenceEntity	[ReferenceGeneProduct:uniprot:A0A286ZYS4] UniProt:A0A286ZYS4
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:49633] Sus scrofa
stId	R-SSC-8848000
startCoordinate	1

(output)	[Reaction:R-SSC-8849435] PTPN1 dephosphorylates PTK6
(activeUnit)	[CatalystActivity:10534892] protein tyrosine kinase activity of HBEGF:EGFR:p-Y525-GPNMB:LINC01139:PTK6:LRRK2 [plasma membrane] [CatalystActivity:10532736] protein tyrosine kinase activity of p-ERBB2 heterodimers:PTK6 [plasma membrane]
(hasComponent)	[Complex:R-SSC-8857567] HBEGF:EGFR:p-Y525-GPNMB:LINC01139:PTK6:LRRK2 [plasma membrane] [Complex:R-SSC-8848002] p-ERBB2 heterodimers:PTK6 [plasma membrane]
(input)	[Reaction:R-SSC-8847995] Activated ERBB2 binds PTK6 (BRK)
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-8848000] PTK6 [cytosol]

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