Reactome | PTEN Regulation

Schema > Pathway > Entries

created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10558483
displayName	PTEN Regulation
eventOf	[Pathway:R-SSC-1257604] PIP3 activates AKT signaling - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-SSC-8943724] Regulation of PTEN gene transcription - Sus scrofa [Pathway:R-SSC-8948747] Regulation of PTEN localization - Sus scrofa [Pathway:R-SSC-8948751] Regulation of PTEN stability and activity - Sus scrofa
inferredFrom	[Pathway:R-HSA-6807070] PTEN Regulation - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	PTEN Regulation
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49633] Sus scrofa
stId	R-SSC-6807070
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SSC-1257604] PIP3 activates AKT signaling
(inferredTo)	[Pathway:R-HSA-6807070] PTEN Regulation