Reactome | APAF1:ATP:CYCS heptamer:CASP9 [cytosol]

Schema > Complex > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-SSC-6804605] APAF1:CYCS:ATP:APIP [cytosol] - Sus scrofa
consumedByEvent	[Reaction:R-SSC-6804596] APAF1:CYCS binds APIP - Sus scrofa [Reaction:R-SSC-9627056] Procaspase 9 forms dimer - Sus scrofa [Reaction:R-SSC-9627089] CASP9 is phosphorylated at T412 - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10455339
displayName	APAF1:ATP:CYCS heptamer:CASP9 [cytosol]
hasComponent	7 × [Complex:R-SSC-6804555] APAF1:ATP:CYCS [cytosol] 4 × [EntityWithAccessionedSequence:R-SSC-57033] CASP9 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-6804619] APAF1:ATP:CYCS heptamer:CASP9 [cytosol] - Homo sapiens
maxDepth	4
name	APAF1:ATP:CYCS heptamer:CASP9
producedByEvent	[Reaction:R-SSC-114256] CYCS:APAF1 binds procaspase-9 - Sus scrofa
schemaClass	Complex
species	[Species:49633] Sus scrofa
stId	R-SSC-6804619
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-SSC-9627089] CASP9 is phosphorylated at T412 [Reaction:R-SSC-6804596] APAF1:CYCS binds APIP [Reaction:R-SSC-9627056] Procaspase 9 forms dimer
(hasComponent)	[Complex:R-SSC-6804605] APAF1:CYCS:ATP:APIP [cytosol]
(output)	[Reaction:R-SSC-114256] CYCS:APAF1 binds procaspase-9
(inferredTo)	[Complex:R-HSA-6804619] APAF1:ATP:CYCS heptamer:CASP9 [cytosol]

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