Reactome | APAF1:ATP:CYCS heptamer:CASP9 [cytosol]

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APAF1:ATP:CYCS heptamer:CASP9 [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-6804605] APAF1:CYCS:ATP:APIP [cytosol] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-6804596] APAF1:CYCS binds APIP - Homo sapiens [Reaction:R-HSA-9627056] Procaspase 9 forms dimer - Homo sapiens [Reaction:R-HSA-9627089] CASP9 is phosphorylated at T412 - Homo sapiens
created	[InstanceEdit:6804583] Shamovsky, Veronica, 2015-10-13
dbId	6804619
displayName	APAF1:ATP:CYCS heptamer:CASP9 [cytosol]
hasComponent	7 × [Complex:R-HSA-6804555] APAF1:ATP:CYCS [cytosol] 4 × [EntityWithAccessionedSequence:R-HSA-57033] CASP9(1-416) [cytosol]
inDisease	false
inferredTo	[Complex:R-MMU-6804619] APAF1:ATP:CYCS heptamer:CASP9 [cytosol] - Mus musculus [Complex:R-RNO-6804619] APAF1:ATP:CYCS heptamer:CASP9 [cytosol] - Rattus norvegicus [Complex:R-CFA-6804619] APAF1:ATP:CYCS heptamer:CASP9 [cytosol] - Canis familiaris [Complex:R-BTA-6804619] APAF1:ATP:CYCS heptamer:CASP9 [cytosol] - Bos taurus [Complex:R-SSC-6804619] APAF1:ATP:CYCS heptamer:CASP9 [cytosol] - Sus scrofa [Complex:R-DRE-6804619] APAF1:ATP:CYCS heptamer:CASP9 [cytosol] - Danio rerio [Complex:R-XTR-6804619] APAF1:ATP:CYCS heptamer:CASP9 [cytosol] - Xenopus tropicalis [Complex:R-GGA-6804619] APAF1:ATP:CYCS heptamer:CASP9 [cytosol] - Gallus gallus [Complex:R-DME-6804619] APAF1:ATP:CYCS heptamer:CASP9 [cytosol] - Drosophila melanogaster
isChimeric	false
literatureReference	[LiteratureReference:6804597] Structure of an apoptosome-procaspase-9 CARD complex [LiteratureReference:9627385] A near atomic structure of the active human apoptosome
maxDepth	4
modified	[InstanceEdit:9627414] Shamovsky, Veronica, 2018-11-02
name	APAF1:ATP:CYCS heptamer:CASP9
producedByEvent	[Reaction:R-HSA-114256] CYCS:APAF1 binds procaspase-9 - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-6804619

Referrals

(input)	[Reaction:R-HSA-9627089] CASP9 is phosphorylated at T412 [Reaction:R-HSA-6804596] APAF1:CYCS binds APIP [Reaction:R-HSA-9627056] Procaspase 9 forms dimer
(hasComponent)	[Complex:R-HSA-6804605] APAF1:CYCS:ATP:APIP [cytosol]
(output)	[Reaction:R-HSA-114256] CYCS:APAF1 binds procaspase-9

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