Reactome | TP53 Regulates Transcription of Cell Cycle Genes

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TP53 Regulates Transcription of Cell Cycle Genes Show undefined attributes

created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10555597
displayName	TP53 Regulates Transcription of Cell Cycle Genes
eventOf	[Pathway:R-SSC-3700989] Transcriptional Regulation by TP53 - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:22659] DNA damage response, signal transduction by p53 class mediator
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-SSC-6804116] TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest - Sus scrofa [Pathway:R-SSC-6804114] TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest - Sus scrofa [Pathway:R-SSC-6804115] TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain - Sus scrofa
inferredFrom	[Pathway:R-HSA-6791312] TP53 Regulates Transcription of Cell Cycle Genes - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	TP53 Regulates Transcription of Cell Cycle Genes
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49633] Sus scrofa
stId	R-SSC-6791312
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-3700989] Transcriptional Regulation by TP53
(hasEncapsulatedEvent)	[Pathway:R-SSC-6804759] Regulation of TP53 Activity through Association with Co-factors
(inferredTo)	[Pathway:R-HSA-6791312] TP53 Regulates Transcription of Cell Cycle Genes

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