Reactome | NAPSA, CTSH, PGA3-5 cleave pro-SFTPC

Schema > Reaction > Entries

NAPSA, CTSH, PGA3-5 cleave pro-SFTPC Show undefined attributes

catalystActivity	[CatalystActivity:10519891] peptidase activity of NAPSA, CTSH, PGA3-5 [multivesicular body lumen]
category	transition
compartment	[Compartment:3828046] multivesicular body lumen
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10520140
displayName	NAPSA, CTSH, PGA3-5 cleave pro-SFTPC
eventOf	[Pathway:R-SSC-5683826] Surfactant metabolism - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5685902] NAPSA, CTSH, PGA3-5 cleave pro-SFTPC - Homo sapiens
input	[SimpleEntity:R-ALL-5685882] H2O [multivesicular body lumen] [EntityWithAccessionedSequence:R-SSC-5685298] SP-C [multivesicular body lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	NAPSA, CTSH, PGA3-5 cleave pro-SFTPC
output	[EntityWithAccessionedSequence:R-SSC-5685899] SP-C [multivesicular body lumen] [EntityWithAccessionedSequence:R-SSC-5685871] SP-C [multivesicular body lumen]
precedingEvent	[BlackBoxEvent:R-SSC-5684868] pro-SFTPC translocates from ER membrane to multivesicle body - Sus scrofa
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-5685902
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-5683826] Surfactant metabolism
(inferredTo)	[Reaction:R-HSA-5685902] NAPSA, CTSH, PGA3-5 cleave pro-SFTPC

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