Reactome | phospho-p-T774-PKN1 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

catalystActivities	[CatalystActivity:10518342] protein serine/threonine kinase activity of p-T774-PKN1 [cytosol]
compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-SSC-5625734] p-T774-PKN1:AR:Androgen [cytosol] - Sus scrofa
consumedByEvent	[Reaction:R-SSC-5625717] Phosphorylated PKN1 binds androgen receptor (AR) - Sus scrofa [Reaction:R-SSC-5671737] p-T774-PKN1 binds CDC25C - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10515574
displayName	phospho-p-T774-PKN1 [cytosol]
endCoordinate	942
hasModifiedResidue	[ModifiedResidue:10515572] O-phospho-L-threonine at 774 (in Homo sapiens)
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-5623651] p-T774-PKN1 [cytosol] - Homo sapiens
maxDepth	1
memberOf	[CandidateSet:R-SSC-5623659] p-T774-PKN1,p-T816-PKN2,p-T718-PKN3 [cytosol] - Sus scrofa
name	phospho-p-T774-PKN1 F1SCG1
producedByEvent	[Reaction:R-SSC-5671749] p-T774-PKN1 phosphorylates CDC25C - Sus scrofa
referenceEntity	[ReferenceGeneProduct:uniprot:F1SCG1] UniProt:F1SCG1
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:49633] Sus scrofa
stId	R-SSC-5623651
startCoordinate	2

(physicalEntity)	[CatalystActivity:10518342] protein serine/threonine kinase activity of p-T774-PKN1 [cytosol]
(input)	[Reaction:R-SSC-5625717] Phosphorylated PKN1 binds androgen receptor (AR) [Reaction:R-SSC-5671737] p-T774-PKN1 binds CDC25C
(hasComponent)	[Complex:R-SSC-5625734] p-T774-PKN1:AR:Androgen [cytosol] [Complex:R-SSC-5671748] p-T774-PKN1:CDC25C [cytosol]
(output)	[Reaction:R-SSC-5671749] p-T774-PKN1 phosphorylates CDC25C
(activeUnit)	[CatalystActivity:10518332] protein serine/threonine kinase activity of p-T774-PKN1:CDC25C [cytosol]
(hasMember)	[CandidateSet:R-SSC-5623659] p-T774-PKN1,p-T816-PKN2,p-T718-PKN3 [cytosol]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-5623651] p-T774-PKN1 [cytosol]

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