Reactome | RPA1 binds HSF1

Schema > Reaction > Entries

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10512948
displayName	RPA1 binds HSF1
eventOf	[Pathway:R-SSC-3371453] Regulation of HSF1-mediated heat shock response - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5333051] RPA1 binds HSF1 - Homo sapiens
input	[Complex:R-SSC-4793790] HSF1 trimer [nucleoplasm] [Complex:R-SSC-68462] RPA heterotrimer [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	RPA1 binds HSF1
output	[Complex:R-SSC-5333048] HSF1:RPA [nucleoplasm]
precedingEvent	[Reaction:R-SSC-5082391] Trimerization of HSF1 in the nucleus - Sus scrofa
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-5333051
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SSC-3371453] Regulation of HSF1-mediated heat shock response
(inferredTo)	[Reaction:R-HSA-5333051] RPA1 binds HSF1