Reactome | phospho-PXN [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-SSC-8848613] p-Y31,Y118-PXN:CRK:DOCK180:ELMO1,ELMO2 [cytosol] - Sus scrofa [Complex:R-SSC-5218756] VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] - Sus scrofa
consumedByEvent	[Reaction:R-SSC-8848611] Phosphorylated PXN recruits the CRK complex - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10511976
displayName	phospho-PXN [cytosol]
endCoordinate	591
hasModifiedResidue	[ModifiedResidue:10511973] O4'-phospho-L-tyrosine at 31 (in Homo sapiens) [ModifiedResidue:10511974] O4'-phospho-L-tyrosine at 118 (in Homo sapiens)
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-5218693] p-Y31,Y118-PXN [cytosol] - Homo sapiens
maxDepth	1
name	phospho-PXN p-Y31,Y118-PXN A0A5G2RG25
producedByEvent	[Reaction:R-SSC-8848606] PTK6 phosphorylates PXN - Sus scrofa
referenceEntity	[ReferenceGeneProduct:uniprot:A0A5G2RG25] UniProt:A0A5G2RG25
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:49633] Sus scrofa
stId	R-SSC-5218693
startCoordinate	1

(hasComponent)	[Complex:R-SSC-5218756] VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] [Complex:R-SSC-8848613] p-Y31,Y118-PXN:CRK:DOCK180:ELMO1,ELMO2 [cytosol]
(input)	[Reaction:R-SSC-8848611] Phosphorylated PXN recruits the CRK complex
(output)	[Reaction:R-SSC-8848606] PTK6 phosphorylates PXN
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-5218693] p-Y31,Y118-PXN [cytosol]

Cite Us!