Reactome | Homologues of GH1 [extracellular region]

Schema > DefinedSet > Entries

compartment	[Compartment:984] extracellular region
componentOf	[Complex:R-SSC-1169232] Growth Hormone:p(Y332,487,627)-Growth Hormone Receptor-p(Y1007)-JAK2 dimer [plasma membrane] - Sus scrofa [Complex:R-SSC-982813] Growth Hormone: Growth Hormone Receptor-JAK2 dimer [plasma membrane] - Sus scrofa
consumedByEvent	[Polymerisation:R-SSC-982765] Growth hormone forms dimers and oligomers - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10477071
displayName	Homologues of GH1 [extracellular region]
hasMember	[EntityWithAccessionedSequence:R-SSC-422070] GH1 [extracellular region] - Sus scrofa [EntityWithAccessionedSequence:R-SSC-422070-2] GH1 [extracellular region] - Sus scrofa
inDisease	false
inferredFrom	[DefinedSet:R-HSA-982814] Growth Hormone [extracellular region] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-5622079] CSH1 [extracellular region] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-982809] GH2 [extracellular region] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-422070] GH1 [extracellular region] - Homo sapiens
maxDepth	2
memberOf	[DefinedSet:R-SSC-1172021] Prolactin receptor ligands [extracellular region] - Sus scrofa
name	Homologues of GH1
negativelyRegulates	[NegativeRegulation:10477075] Negative regulation by 'GH1 [extracellular region]'
repeatedUnitOf	[Polymer:R-SSC-982799] Growth hormone oligomer [extracellular region] - Sus scrofa
schemaClass	DefinedSet
species	[Species:49633] Sus scrofa
stId	R-SSC-422070-3

(hasComponent)	[Complex:R-SSC-1169232] Growth Hormone:p(Y332,487,627)-Growth Hormone Receptor-p(Y1007)-JAK2 dimer [plasma membrane] [Complex:R-SSC-1168898] Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer [plasma membrane] [Complex:R-SSC-982813] Growth Hormone: Growth Hormone Receptor-JAK2 dimer [plasma membrane] [Complex:R-SSC-1172022] Placental lactogen [extracellular region]
(input)	[Polymerisation:R-SSC-982765] Growth hormone forms dimers and oligomers
(repeatedUnit)	[Polymer:R-SSC-982799] Growth hormone oligomer [extracellular region]
(hasMember)	[DefinedSet:R-SSC-1172021] Prolactin receptor ligands [extracellular region]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-5622079] CSH1 [extracellular region] [DefinedSet:R-HSA-982814] Growth Hormone [extracellular region] [EntityWithAccessionedSequence:R-HSA-982809] GH2 [extracellular region] [EntityWithAccessionedSequence:R-HSA-422070] GH1 [extracellular region]
(regulator)	[NegativeRegulation:10477075] Negative regulation by 'GH1 [extracellular region]'

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