Reactome | KMT5A [nucleoplasm]

Schema > EntityWithAccessionedSequence > Entries

catalystActivities	[CatalystActivity:10514145] histone H4 methyltransferase activity of SETD8 [nucleoplasm] [CatalystActivity:10530257] lysine N-methyltransferase activity of SETD8 [nucleoplasm] [CatalystActivity:10503137] histone H4K20 methyltransferase activity of SETD8 [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-SSC-9931110] SET8:TWIST1:CDH1 gene [nucleoplasm] - Sus scrofa
consumedByEvent	[Reaction:R-SSC-9765788] TWIST1 recruits SETD8 to CDH1 gene promoter - Sus scrofa [Reaction:R-SSC-9765791] ZEB1 recruits SETD8 to CDH1 gene promoter - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10503136
displayName	KMT5A [nucleoplasm]
endCoordinate	393
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-417142] SETD8 [nucleoplasm] - Homo sapiens
maxDepth	1
name	KMT5A SETD8 A0A5K1VJN6
referenceEntity	[ReferenceGeneProduct:uniprot:A0A5K1VJN6] UniProt:A0A5K1VJN6
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:49633] Sus scrofa
stId	R-SSC-417142
startCoordinate	1

(physicalEntity)	[CatalystActivity:10514145] histone H4 methyltransferase activity of SETD8 [nucleoplasm] [CatalystActivity:10530257] lysine N-methyltransferase activity of SETD8 [nucleoplasm] [CatalystActivity:10503137] histone H4K20 methyltransferase activity of SETD8 [nucleoplasm]
(input)	[Reaction:R-SSC-9765788] TWIST1 recruits SETD8 to CDH1 gene promoter [Reaction:R-SSC-9765791] ZEB1 recruits SETD8 to CDH1 gene promoter
(hasComponent)	[Complex:R-SSC-9931110] SET8:TWIST1:CDH1 gene [nucleoplasm] [Complex:R-SSC-9931117] SETD8:ZEB1:CDH1 gene [nucleoplasm]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-417142] SETD8 [nucleoplasm]

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