Reactome | PDGF binds to extracellular matrix proteins

Schema > Reaction > Entries

PDGF binds to extracellular matrix proteins Show undefined attributes

category	binding
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10474055
displayName	PDGF binds to extracellular matrix proteins
eventOf	[Pathway:R-SSC-186797] Signaling by PDGF - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-382054] PDGF binds to extracellular matrix proteins - Homo sapiens
input	[DefinedSet:R-SSC-381946] Extracellular matrix ligands [extracellular region] 2 × [DefinedSet:R-SSC-381934] PDGF A and B chains with retention motif [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	PDGF binds to extracellular matrix proteins
output	[Complex:R-SSC-381952] PDGF A and B chains:ECM complex [extracellular region]
precedingEvent	[Reaction:R-SSC-186785] PDGF-AA clevage by Furin - Sus scrofa
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-382054
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-186797] Signaling by PDGF
(inferredTo)	[Reaction:R-HSA-382054] PDGF binds to extracellular matrix proteins

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