Reactome | AGT [extracellular region]

compartment	[Compartment:984] extracellular region
componentOf	[Complex:R-SSC-389876] AGTR1:AGT(25-32) [plasma membrane] - Sus scrofa
consumedByEvent	[Reaction:R-SSC-2022399] ENPEP:Zn2+ hydrolyzes AGT(25-32) (Angiotensin-(1-8)) to AGT(26-32) (Angiotensin-(2-8)) - Sus scrofa [Reaction:R-SSC-2022379] ACE2(18-805):Zn2+ hydrolyzes AGT(25-32) (Angiotensin-(1-8)) to AGT(25-31) (Angiotensin-(1-7)) - Sus scrofa [Reaction:R-SSC-9615348] AGT(25-32) binds to AGTR2 - Sus scrofa [Reaction:R-SSC-374173] AGT(25-32) binds to AGTR1 - Sus scrofa
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10471233
displayName	AGT [extracellular region]
endCoordinate	32
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-374187] AGT(25-32) [extracellular region] - Homo sapiens
maxDepth	1
name	AGT AGT(25-32) A0A287AJ51
producedByEvent	[Reaction:R-SSC-2022411] Cathepsin G hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) - Sus scrofa [Reaction:R-SSC-2022381] Cathepsin Z (Cathepsin X) hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) - Sus scrofa [Reaction:R-SSC-2022383] Chymase hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) - Sus scrofa [Reaction:R-SSC-2022405] ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) - Sus scrofa [Reaction:R-SSC-2065355] Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) - Sus scrofa
referenceEntity	[ReferenceGeneProduct:uniprot:A0A287AJ51] UniProt:A0A287AJ51
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:49633] Sus scrofa
stId	R-SSC-374187
startCoordinate	25

(input)	[Reaction:R-SSC-2022399] ENPEP:Zn2+ hydrolyzes AGT(25-32) (Angiotensin-(1-8)) to AGT(26-32) (Angiotensin-(2-8)) [Reaction:R-SSC-2022379] ACE2(18-805):Zn2+ hydrolyzes AGT(25-32) (Angiotensin-(1-8)) to AGT(25-31) (Angiotensin-(1-7)) [Reaction:R-SSC-9615348] AGT(25-32) binds to AGTR2 [Reaction:R-SSC-374173] AGT(25-32) binds to AGTR1
(output)	[Reaction:R-SSC-2022411] Cathepsin G hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) [Reaction:R-SSC-2022381] Cathepsin Z (Cathepsin X) hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) [Reaction:R-SSC-2022383] Chymase hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) [Reaction:R-SSC-2022405] ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) [Reaction:R-SSC-2065355] Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8))
(hasComponent)	[Complex:R-SSC-389876] AGTR1:AGT(25-32) [plasma membrane] [Complex:R-SSC-389873] AGTR2:AGT(25-32) [plasma membrane]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-374187] AGT(25-32) [extracellular region]

AGT [extracellular region] Show undefined attributes

Referrals